Ronald J Quinn & Miaomiao Liu research group

2023

Journal of Natural Products

Discovery of Anti-SARS-CoV-2 Nsp9 Binders from Natural Products by a Native Mass Spectrometry Approach

Ronald J. Quinn, Tin Mak, Dene R. Littler, Jamie Rossjohn, and Miaomiao Liu*

Protein & Cell

A hnRNPA2B1 agonist effectively inhibits HBV and SARS-CoV-2 omicron in vivo

Daming Zuo, Yu Chen, Jian-piao Cai, Hao-Yang Yuan, Jun-Qi Wu, Yue Yin, Jing-Wen Xie, Jing-Min Lin, Jia Luo, Yang Feng, Long-Jiao Ge, Jia Zhou, Ronald J. Quinn, San-Jun Zhao, Xing Tong, Dong-Yan Jin, Shuofeng Yuan*, Shao-Xing Dai3*, and Min Xu*

Pharmacological Reviews

Potassium Channels in Parkinson’s Disease: Potential Roles in Its Pathogenesis and Innovative Molecular Targets for Treatment

Xiaoyi Chen, Yunjiang Feng, Ronald J. Quinn, Dean L. Pountney, Des R. Richardson,* George D. Mellick*, and Linlin Ma*

Australian Journal of Chemistry

The mechanism of cleavage of Evans chiral auxiliaries by LiOOH: origins of the different regioselectivities obtained with LiOH, LiOOH, LiOBn and LiSBn

Ka Ho Chow, Ronald J. Quinn, Ian D. Jenkins*, and Elizabeth H. Krenske*

ACS Pharmacology & Translational Science

Drug-Repurposing Screening Identifies a Gallic Acid Binding Site on SARS-CoV-2 Non-structural Protein 7

Yushu Gu, Miaomiao Liu, Bart L. Staker, Garry W. Buchko, and Ronald J. Quinn*

2022

Analytical Chemistry

Quaternized Acridine Maleimide MALDI Probe Enables Mass Spectrometry Imaging of Thiols

Zhenghua Ma, Jie Yuan, Jianfeng Xu, Lizhi Li, Chunping Tang, Lu Chang, Ronald J Quinn, Lunxiu Qin*, Jia Liu*, and Yang Ye*

Frontiers in Analytical Science

Metabolite-protein interactions: Native mass spectrometry and collision induced affinity selection mass spectrometry in natural product screening

Yushu Gu, Miaomiao Liu and Ronald J. Quinn*

Natural Product Report

Natural product-based PROteolysis TArgeting Chimeras (PROTACs)

Miaomiao Liu, Alexander P. Martyn and Ronald J. Quinn*

ACS Bio Med Chem Au

Collision-Induced Affinity Selection Mass Spectrometry for Identification of Ligands

Tin Mak, Jamie Rossjohn, Dene R. Littler, Miaomiao Liu*, and Ronald J. Quinn*

ACS OMEGA

Identifying New Ligands for JNK3 by Fluorescence Thermal Shift Assays and Native Mass Spectrometry

Chongyun Cheng, Miaomiao Liu, Xiaoqin Gao, Dong Wu, Mengchen Pu, Jun Ma, Ronald J. Quinn*, Zhicheng Xiao*, and Zhijie Liu*

ACS OMEGA

Binding Studies of the Prodrug HAO472 to SARS-Cov-2 Nsp9 and Variants

Miaomiao Liu, Dene R. Littler, Jamie Rossjohn, and Ronald J Quinn*

Natural Product Reports

Anti-mycobacterial natural products and mechanisms of action

Jianying Han, Xueting Liu, Lixin Zhang, Ronald J Quinn* and Yunjiang Feng*

2021

ACS OMEGA

Styracifoline from the Vietnamese Plant Desmodium styracifolium: A Potential Inhibitor of Diabetes-Related and Thrombosis-Based Proteins

Tran TD, Bui TQ, Le TA, Nguyen MT, Nguyen TTH, Pham NH, Phan MN, Healy PC, Pham NB, Quinn RJ, Phan TQ, Nguyen TT, Nguyen HN, Le NH, Phung T, Nguyen TAN

Journal of Biological Chemistry

A natural product compound inhibits coronaviral replication in vitro by binding to the conserved Nsp9 SARS-CoV-2 protein

Dene R. Littler*, Miaomiao Liu, Julie L. McAuley, Shea A. Lowery, Patricia T. Illing, Benjamin S. Gully,

Anthony W. Purcell, Indu R. Chandrashekaran, Stanley Perlman, Damian F. J. Purcell, Ronald J. Quinn* and Jamie Rossjohn*

Journal of Natural Products

Antimicrobial Benzyltetrahydroisoquinoline-Derived Alkaloids from the Leaves of Doryphora aromatica

Miaomiao Liu*, Jianying Han, Yunjiang Feng, Gordon Guymer, Paul I. Forster, and Ronald J. Quinn*

International Journal for Parasitology: Drugs and Drug Resistance

Antiplasmodial activity of the natural product compounds alstonine and himbeline

M.S.J. Arnold, J.R. Macdonald, R.J. Quinn, T.S. Skinner-Adams, K.T. Andrews, G.M. Fisher*

Redox Biology

Calcium channels and iron metabolism: A redox catastrophe in Parkinson's disease and an innovative path to novel therapies?

Matthew K. Boag, Linlin Ma, George D. Mellick, Dean L. Pountney, Yunjiang Feng, Ronald J. Quinn, Alan Wee-Chung Liew, Mahendiran Dharmasivam, Mahan Gholam Azad, Rizwana Afroz, Des R. Richardson*

Scientific Reports

Development of a target identification approach using native mass spectrometry

Miaomiao Liu, Wesley C. Van Voorhis and Ronald J. Quinn*

Applied Microbiology and Biotechnology

Genome-guided investigation of anti-inflammatory sesterterpenoids with 5-15 trans-fused ring system from phytopathogenic fungi

Lan Jiang, Guoliang Zhu, Jianying Han, Chengjian Hou, Xue Zhang, Zhixin Wang, Weize Yuan, Kangjie Lv, Zhanren Cong, Xinye Wang, Xiangyin Chen, Loganathan Karthik, Huanting Yang, Xuyuan Wang, Gaoyi Tan, Guang Liu, Liya Zhao, Xuekui Xia, Xiangyang Liu, Shushan Gao, Lei Ma, Mei Liu, Biao Ren, Huanqin Dai, Ronald J. Quinn, Tom Hsiang*, Jingyu Zhang*, Lixin Zhang, Xueting Liu*

ChemMedChem

Native Mass Spectrometry for the Study of PROTAC GNE-987-Containing Ternary Complexes

Louise M Sternicki, Jim Nonomiya, Miaomiao Liu, Melinda M Mulvihill*, Ronald J Quinn*

Redox Biology

Parkinson’s disease: Alterations in iron and redox biology as a key to unlock therapeutic strategies

L. Ma, M. Gholam Azad, M. Dharmasivam, V. Richardson, R.J. Quinn, Y. Feng, D.L. Pountney, K.F. Tonissen, G.D. Mellick, I. Yanatori, D.R. Richardson*

Applied Microbiology and Biotechnology

Peculiarities of meroterpenoids and their bioproduction

Jianying Han, Lan Jiang, Lixin Zhang, Ronald J. Quinn, Xueting Liu and Yunjiang Feng*

2020

Comprehensive Natural Products II

3.07 - The Identification of Bioactive Natural Products by High Throughput Screening (HTS)

Vicky M. Avery, David Camp, Anthony R. Carroll, Ian D. Jenkins and Ronald J.Quinn

Journal of Natural Products

A Grand Challenge. 3. Unbiased Phenotypic Function of Metabolites from Australia Plants Gloriosa superba and Alangium villosum against Parkinson’s Disease

Dongdong Wang, Mariyam Murtaza, Stephen A. Wood, George D. Mellick, William Gang Miao, Gordon P. Guymer, Paul I. Forster, Yunjiang Feng* and Ronald J. Quinn*

Marine Drugs

A Phenotarget Approach for Identifying an Alkaloid Interacting with the Tuberculosis Protein Rv1466

Yan Xie, Yunjiang Feng, Angela Di Capua, Tin Mak, Garry W. Buchko, Peter J. Myler, Miaomiao Liu and Ronald J. Quinn*

Acta Pharmacologica Sinica

Advances in the development of imaging probes and aggregation inhibitors for alpha-synuclein

Ming-ming Xu, Philip Ryan, Santosh Rudrawar, Ronald J Quinn, Hai-yan Zhang and George D Mellick*

ACS OMEGA

Analysis of Approaches to Anti-tuberculosis Compounds

Sara Motamen and Ronald J. Quinn*

Molecules

Discovery of a Natural Product That Binds to the Mycobacterium tuberculosis Protein Rv1466 Using Native Mass Spectrometry

Ali R. Elnaas, Darren Grice, Jianying Han, Yunjiang Feng, Angela Di Capua, Tin Mak, Joseph A. Laureanti, Garry W. Buchko, Peter J. Myler, Gregory Cook, Ronald J. Quinn and Miaomiao Liu*

Applied Microbiology and Biotechnology

Genome-based mining of new antimicrobial meroterpenoids from the phytopathogenic fungus Bipolaris sorokiniana strain 11134

Jianying Han, Jingyu Zhang, Zhijun Song, Guoliang Zhu, Miaomiao Liu, Huanqin Dai, Tom Hsiang, Xueting Liu, Lixin Zhang, Ronald J Quinn* and Yunjiang Feng*

Marine Drugs

Genome-Inspired Chemical Exploration of Marine Fungus Aspergillus fumigatus MF071

Jianying Han, Miaomiao Liu, Ian D. Jenkins, Xueting Liu, Lixin Zhang, Ronald J. Quinn* and Yunjiang Feng*

International Journal of Nanomedicine

Hepatitis C Virus NS3 Protease and Helicase Inhibitors from Red Sea Sponge (Amphimedon) Species in Green Synthesized Silver Nanoparticles Assisted by in Silico Modeling and Metabolic Profiling

Nourhan Hisham Shady, Amira R Khattab, Safwat Ahmed, Miaomiao Liu, Ronald J Quinn, Mostafa A Fouad, Mohamed Salah Kamel, Abdullatif Bin Muhsinah, Markus Krischke, Martin J Mueller and Usama Ramadan Abdelmohsen*

International Journal of Molecular Sciences

Lessons from Exploring Chemical Space and Chemical Diversity of Propolis Components

Trong D. Tran*, Steven M. Ogbourne, Peter R. Brooks, Norberto Sánchez-Cruz, José L. Medina-Franco and Ronald J. Quinn*

RSC Advances

Marine natural products from sponges (Porifera) of the order Dictyoceratida (2013 to 2019); a promising source for drug discovery

Enas Reda Abdelaleem, Mamdouh Nabil Samy, Samar Yehia Desoukey, Miaomiao Liu, Ronald J. Quinn and Usama Ramadan Abdelmohsen*

Metabolites

Testicular Caspase-3 and β-Catenin Regulators Predicted via Comparative Metabolomics and Docking Studies

Mohammed S. Hifnawy, Mahmoud A. Aboseada, Hossam M. Hassan, Asmaa M. AboulMagd, Adel F. Tohamy, Samraa H. Abdel-Kawi, Mostafa E. Rateb, El Moataz Bellah El Naggar, Miaomiao Liu, Ronald J. Quinn, Hani A. Alhadrami* and Usama Ramadan Abdelmohsen*