• Home
  • Research
    • Research interest
    • Available projects
  • Publication
  • Service
  • People
  • Instruments
    • Natural product chemistry
    • Mass spectrometry
    • Cell culture
  • News
    • 2021
    • 2022
    • 2023
    • 2024
  • More
    • Home
    • Research
      • Research interest
      • Available projects
    • Publication
    • Service
    • People
    • Instruments
      • Natural product chemistry
      • Mass spectrometry
      • Cell culture
    • News
      • 2021
      • 2022
      • 2023
      • 2024
  • Home
  • Research
    • Research interest
    • Available projects
  • Publication
  • Service
  • People
  • Instruments
    • Natural product chemistry
    • Mass spectrometry
    • Cell culture
  • News
    • 2021
    • 2022
    • 2023
    • 2024

Ronald J Quinn & Miaomiao Liu research group

Ronald J Quinn & Miaomiao Liu research groupRonald J Quinn & Miaomiao Liu research groupRonald J Quinn & Miaomiao Liu research group

Decoding the Language of Nature Using Native Mass Spectrometry

Decoding the Language of Nature Using Native Mass SpectrometryDecoding the Language of Nature Using Native Mass SpectrometryDecoding the Language of Nature Using Native Mass SpectrometryDecoding the Language of Nature Using Native Mass SpectrometryDecoding the Language of Nature Using Native Mass Spectrometry

Mass spectrometers

Bruker SolariX 12 Tesla Magnetic Resonance Mass Spectrometer

Features:

  • ESI source
  • High mass resolution >10 million (isotopic resolution) and high mass range acquisition of up to 150 kDa
  • MS/MS analysis with fragmentation techniques that include collision induced dissociation, electron capture dissociation and electron transfer dissociation.

Main applications:

  • Advanced protein analysis including native protein analysis, quantification of protein/ ligand binding affinity, high throughput bioaffinity screening MS/MS analysis.
  • Small molecule analysis.
  • Complex mixtures, such as natural product extracts.

MaXis UHR ESI QTOF Mass Spectrometer

Features:

  • ESI source
  • High-Mass option, easier characterisation of high-molecular weight species and native state protein complexes.
  • Full sensitivity resolution of >80,000.
  • MS/MS analysis with fragmentation technique by collision induced dissociation

Main applications:

  • Small molecule analysis for HRMS measurement.
  • Advanced protein analysis which includes native protein analysis, high throughput bioaffinity screening.

Thermo Fisher Ultimate 3000 RS LCMS UHPLC- ISQ Single Quadrupole

Features:

  • ESI source
  • UHPLC C18 column in use
  • Up to 1250 m/z

Main applications:

  • Routine LCMS analysis of small molecules from fractions, reaction mixtures, purified reaction products, crude extracts

TriVersa NanoMate (Advion)

Features:

  • Chip-based nano-ESI source
  • Automatic injection

Main applications:

  • Coupled with FTMS on various protein analysis

Newomics

Features:

  • Chip-free Nano-ESI source

Main applications:

  • Coupled with FTMS on various protein analysis
  • Coupled with Nano-LC for automatic injections

Copyright © 2022 Ronald J Quinn & Miaomiao Liu research group - All Rights Reserved.


Powered by

This website uses cookies.

We use cookies to analyze website traffic and optimize your website experience. By accepting our use of cookies, your data will be aggregated with all other user data.

Accept